Product Detail

CAS:443-48-1

1.Metronidazole is a nitroimidazole antibiotic, also known as methotrexate, metronidazole, metronidazole, metronidazole, methotrexate, anaerobic microorganisms have a killing effect, it is reduced in the human body when the metabolites generated also has an anti-anaerobic bacterial effect, inhibit the synthesis of deoxyribonucleic acid of bacteria, thereby interfering with the growth of bacteria, reproduction, and ultimately cause bacterial death, anti-anaerobic bacteria Pu include: Bacteroides fragilis, Clostridium (due to The anti-anaerobic bacteria include: Bacteroides fragilis, Clostridium perfringens (named because of the sharp ends of the bacterium), Bacillus tetani, Streptococcus pepticus, Streptococcus pepticus, and JaChemicalbook flagellate. It was initially used to treat trichomoniasis of the vagina with great clinical effectiveness. Later it was discovered that metronidazole could also kill anaerobic bacteria causing oral infections, and in 1978 it was identified by the World Health Organization as a potent drug against anaerobic infections and is widely used for the prevention and treatment of oral anaerobic infections. It is also frequently used in hospitals for the prevention and treatment of respiratory, gastrointestinal, abdominal and pelvic infections caused by anaerobic bacteria, skin and soft tissue infections, bone and joint infections, carditis, sepsis and brain.

2.The mechanism of action is through the inhibition of the redox reaction of the amoeba protozoa, so that the nitrogen chain of the protozoa is broken and the effect. In vitro test proves that at the concentration of 1~2mg/L, the morphological change of ameba of Chemicalbook tissue can occur in 6~20 hours, and all of them can be killed within 24 hours.

3.White or yellowish crystal or crystalline powder; slightly odorous, bitter and slightly salty. Slightly soluble in ethanol, slightly soluble in water or chloroform, very slightly soluble in ether. Methyl Chemicalbook nitrazole is a nitrogen-containing heterocyclic compound with alkalinity and low water solubility. According to the principle of premedication, metronidazole is made into potassium phosphate salt, and the water solubility is increased, which can be used as injection solution.

Application

1.It has been used for the treatment of trichomoniasis since 1959 and for intestinal internal and external amebiasis since 1970, with high efficacy, low toxicity and wide application. It has mutagenic and teratogenic effects in animal experiments.
2.Strong antibacterial effect against most anaerobic bacteria
3.For the treatment of amoebiasis, trichomoniasis and anaerobic infections